In Major League Baseball, a pitcher’s ability to re-enter a game after being removed is governed by specific rules. Generally, once a pitcher is taken out of a game, they cannot return to pitch again in that same game. A common example is when a starting pitcher is relieved due to performance issues; that pitcher is ineligible to pitch later in the contest.
This rule encourages strategic bullpen management and aims to protect player health. It prevents managers from repeatedly using a single pitcher in unconventional ways and ensures that multiple pitchers are utilized throughout a game. Historically, before rule changes, managers sometimes exploited loopholes to gain an advantage, leading to the current restrictions.